Microbial Minutes: Microbiome Disease Databases, HIV Vaccine Trial, and Antibiotic Updates

July 23, 2018

What's hot in the microbial sciences? ASM summarizes microbiology news and reports in Microbial Minutes, a biweekly news roundup. Watch the YouTube session for summaries and major findings, and read the reports and news coverage for yourself below. What should we highlight next time? Leave a suggestion in our comments section!

New Databases Link Microbiome Compositions to Disease

Jackson MA et al. Gut microbiota associations with common diseases and prescription medications in a population-based cohort. Nature Comm. 9:2655. July 9 2018. 

Janssens Y et al. Disbiome database: linking the microbiome to disease. BMC Microbiology 18. June 4 2018.

Candida Drug Tolerance Increases Difficulty of Its Treatment

Rosenberg A et al. Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia.  Nature Comm. 9:2470. June 25 2018.

HIV Vaccine Elicits Strong Immune Response, Enters Phase IIb Trial

Barouch DH et al. Evaluation of a mosaic HIV-1 vaccine in a multicenter, randomized, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (MHP 13-19). Lancet. July 6 2018.

Antibiotic Prescriptions Are a Good Target For Stewardship

Palms DL et al. Comparison of antibiotic prescribing in retail clinics, urgent care centers, emergency departments, and traditional ambulatory care settings in the United States. JAMA Intern Med. July 16 2018. 

Shively NR et al. Prevalence of inappropriate antibiotic  prescribing in primary care clinics within a Veterans Affairs healthcare system. Antimicrobial Agents and Chemotherapy. July 2 2018.

FDA Approves Smallpox Drug

Press Release: FDA approves of the first drug with an indication for treatment of smallpox. July 13 2018. 

Author: Julie Wolf

Julie Wolf
Dr. Julie Wolf is in science communications at Indie Bio, and was a former ASM employee. Follow Julie on Twitter for more ASM and microbiology highlights at @JulieMarieWolf.