Microbial Minutes: New Vaccine Strategies
Research discussed:
Wei X. et al. Biomimetic Micromotor Enables Active Delivery of Antigens for Oral Vaccination. NANOletters. February 6 2019.
Voss J.E. et al. Reprogramming the Antigen Specificity of B Cells using Genome-Editing Technologies. eLife. January 16 2019.
Moffett H.F. et al. B Cells Engineered to Express Pathogen-Specific Antibodies using CRISPR/Cas9 Protect against Infection. bioRxiv. February 6 2019.
Further Reading:
STAT News: https://www.statnews.com/2019/02/19/crispr-might-work-when-vaccines-fail/
The Scientist: https://www.the-scientist.com/news-opinion/tiny--motorized-pill-delivers-vaccine-to-mouse-intestine-65482
Science article on ingestible pill: http://science.sciencemag.org/content/363/6427/611