A Quick Guide to the Significance and Laboratory Identification of Cryptococcus gattii

Jan. 18, 2011

A Quick Guide to the Significance and Laboratory Identification
of Cryptococcus gattii
By Susan M. Butler-Wu Ph.D., D(ABMM) and Ajit P. Limaye M.D.
 
“News you can use”:
  • C. gattii is an emerging agent of cryptococcosis that is indistinguishable from C. neoformans by most routine laboratory tests, e.g. Cryptococcal antigen test, commercial biochemical identification systems for yeast, microscopic morphology, etc.
  • C. gattii infects both immuno-competent and immuno-compromised individuals, and may be associated with worse clinical outcomes. Due to increasing awareness of C. gattii infections, laboratories may be asked to distinguish C. gattii from C. neoformans
  • C. gattii can only be differentiated from C. neoformans by specific biochemical or molecular testing
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