Ariane Briegel, Ph.D. is a professor of Ultrastructural Biology at the Leiden University, and also a co-director at the Netherlands Centre for Electron Nanoscopy (NeCEN). She has over 15 years of experience using cryo-electron microscopy to study bacterial and archaeal ultrastructure. The Briegel laboratory focuses on investigating how microbes sense and respond to their environment. In order to gain insight into the structure and function of the molecular complexes involved in these behaviors, the lab uses electron cryotomography and correlative microscopy methods.