César de la Fuente, Ph.D.

César de la Fuente, Ph.D.

University of Pennsylvania

César de la Fuente, Ph.D. is a Presidential Assistant Professor at the University of Pennsylvania, where he leads the Machine Biology Group whose goal is to combine the power of machines and biology to understand, prevent, and treat infectious diseases. Current application areas in his lab include developing novel approaches for antibiotic discovery, building tools for microbiome engineering, and creating low-cost diagnostics. He pioneered the development of the world’s first antibiotic designed by a computer with efficacy in animal models (Nature Communications 2018), designed pattern recognition algorithms for antibiotic discovery, successfully reprogrammed venoms into novel antimicrobials (PNAS 2020, Nature Comm Biol 2018), created novel resistance-proof antimicrobial materials (ACS Nano 2021), and invented rapid low-cost diagnostics for COVID-19 and other infectious diseases.
 
De la Fuente is an NIH MIRA investigator and a BBRF Young Investigator. He has received recognition and research funding from numerous other groups, such as being recognized by MIT Technology Review in 2019 as one of the world’s top innovators for “digitizing evolution to make better antibiotics.” Most recently, de la Fuente was awarded Princess of Girona Prize for Scientific Research. His scientific discoveries have yielded multiple patents and over 85 peer-reviewed publications, including papers in Nature Communications, PNAS, ACS Nano, Cell, and Nature Communications Biology.