Krisztina M. Papp-Wallace, Ph.D.
Veterans Affairs Northeast Ohio Healthcare System
Krisztina M. Papp-Wallace, Ph.D., is a research scientist at the Veterans Affairs Northeast Ohio Healthcare System and an associate professor in the Department of Medicine Division of Infectious Diseases and HIV Medicine and Department of Biochemistry at Case Western Reserve University.
She completed her doctorate in pharmacology at Case Western Reserve University, followed by postdoctoral training in microbiology and antimicrobial resistance at Veterans Affairs Northeast Ohio Healthcare System in Cleveland, Ohio, under the direction of Dr. Robert A. Bonomo. She began her career studying magnesium homeostasis in Salmonella Typhimurium, including research on the regulation of the CorA, MgtA and MgtB magnesium transporters and their impact on virulence.
Papp-Wallace's research interests have transitioned to understanding mechanisms of antimicrobial resistance in gram-negative bacteria and strategies to overcome resistance. She leads projects focused on structure-function relationships of clinically important β-lactamases from gram-negative bacteria using microbiological and biochemical testing and structural biology. She has identified several novel antibiotic combinations to target difficult-to-treat gram-negative bacteria, including Pseudomonas aeruginosa and Burkholderia cepacia complex. She has established national and international collaborations with members of academia and industry to examine the role of antimicrobial resistance in gram-negative bacteria on a global scale.
She completed her doctorate in pharmacology at Case Western Reserve University, followed by postdoctoral training in microbiology and antimicrobial resistance at Veterans Affairs Northeast Ohio Healthcare System in Cleveland, Ohio, under the direction of Dr. Robert A. Bonomo. She began her career studying magnesium homeostasis in Salmonella Typhimurium, including research on the regulation of the CorA, MgtA and MgtB magnesium transporters and their impact on virulence.
Papp-Wallace's research interests have transitioned to understanding mechanisms of antimicrobial resistance in gram-negative bacteria and strategies to overcome resistance. She leads projects focused on structure-function relationships of clinically important β-lactamases from gram-negative bacteria using microbiological and biochemical testing and structural biology. She has identified several novel antibiotic combinations to target difficult-to-treat gram-negative bacteria, including Pseudomonas aeruginosa and Burkholderia cepacia complex. She has established national and international collaborations with members of academia and industry to examine the role of antimicrobial resistance in gram-negative bacteria on a global scale.