Browse By Topic Drug Resistance

New research suggests that phage superspreaders may help drive bacterial evolution in natural environments.

Colistin resistance is now a worldwide issue. New ASM Journal articles uncover the molecular mechanism of colistin resistance, and uncover a natural product that may act to reverse resistance and render colistin once more effective.

Mutations that arise naturally are generally thought to require selection to become part of a population. A new Antimicrobial Agents and Chemotherapy study challenges that thought, by demonstrating the evolution of drug resistance in bacterial lineages never exposed to drugs. This study demonstrates the importance of stewardship in all cases, both transmission of already-resistant strains or selection for newly adapted strains.