Engineered bacteria could help people digest an essential nutrient when they can't digest it themselves!
Microbe of the episode
Microbe of the episode: Kadipiro virus
- Can the Microbiome Deliver? A Proof-of-Concept Engineered E. coli PKU Therapeutic (paywall)
- Science-Based Medicine blog article about phenylketonuria, Synlogic, and engineering bacteria to treat this disorder, with lots of good detail
In an effort to provide better options for PKU, scientists at Synlogic, Inc have created a strain of Escherichia coli that produces phenylalanine-degrading enzymes in the gut. The hope is that ingesting this bacterium could allow PKU patients to be less restrictive with their diet.
Other interesting stories
- Probiotic molecule induces protection in mice against viral brain infection
- E. coli growing with artificially synthesized genome (Extra information)