Adding tags to proteins to increase their degradation can help engineered bacteria grow and survive better under various conditions!
Microbe of the episode:
Lactococcus virus sk1
In this study, a solution to this issue was tested using protein tags that signal the bacterial enzymes to degrade the engineered proteins. A variety of tags allowed for a variety of rates of degradation, allowing engineers to tune in the ideal rate. Bacteria with these engineered tags grew better in nutrient limited conditions than those without.