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Intro music is by Ronald Jenkees.
Send your virology questions and comments to twiv@microbe.tv.
Paul and Theodora return to TWiV to explain their research on determining the number of neutralizing epitopes on the SARS-CoV-2 spike that are recognized by antibodies, and engineering of a polymutant spike with twenty amino acid changes that demonstrates the high genetic barrier to escape from convalescent serum.
Guests: Paul Bieniasz and Theodora Hatiziiouannou
Links for this episode
- High genetic barrier for SARS-CoV-2 antibody escape (bioRxiv) 4:46
- Enhanced antibody one year after COVID-19 (Nature)
- Letters read on TWiV 796 1:49:14
- Timestamps by Jolene. Thanks!
Weekly Science Picks 1:37:12
Dickson – NIF and Photon Science: fusion reaction generates 1.3 MJ
Brianne – The PCR Song
Rich – 1) How Boston Dynamics’ Spot Robot Works! 2) Inside the lab: How does Atlas work? 3) Atlas | Partners in Parkour
Theodora – Kevin Parry turning into random objects
Vincent – Lex Fridman