Episode Summary

Paul and Theodora return to TWiV to explain their research on determining the number of neutralizing epitopes on the SARS-CoV-2 spike that are recognized by antibodies, and engineering of a polymutant spike with twenty amino acid changes that demonstrates the high genetic barrier to escape from convalescent serum.


Paul Bieniasz and Theodora Hatiziiouannou.

Links for This Episode

Weekly Science Picks 1:37:12

DicksonNIF and Photon Science: fusion reaction generates 1.3 MJ.
BrianneThe PCR Song.
Rich – 1) How Boston Dynamics’ Spot Robot Works! 2) Inside the lab: How does Atlas work? 3) Atlas | Partners in Parkour.
Theodora – Kevin Parry turning into random objects.
VincentLex Fridman.

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Intro music is by Ronald Jenkees.