Urinary Tract Infections: Molecular Pathogenesis and Clinical Management Now Available from ASM Press

Feb. 15, 2017

\Washington, DC – February 15, 2017 – The second edition of ASM Press’ comprehensive overview of clinically important UTIs, Urinary Tract Infections: Molecular Pathogenesis and Clinical Management, is now available, capturing the latest research on UTIs. Urinary tract infections (UTIs) continue to rank among the most common infectious diseases of humans, despite remarkable progress in the ability to detect and treat them. Recurrent UTIs represent a growing threat as antibiotic-resistant organisms and infection-prone populations increase.

Urinary Tract Infections: Molecular Pathogenesis and Clinical Management brings the scientific community up to date on UTI infection research that has occurred in the nearly two decades since the first edition, and covers these critical topic areas:

• Clinical aspects of urinary tract infections, including anatomy, diagnosis, and management, featuring chapters on the vaginal microbiome as well as asymptomatic bacteriuria, prostatitis, and urosepsis.

• The origins and virulence mechanisms of the bacteria responsible for most UTIs, including uropathogenic Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae.

• The host immune response to UTIs, the rise of antibiotic-resistant strains, and the future of therapeutics.

This essential reference serves as both a resource and a stimulus for future research endeavors for anyone with an interest in understanding these important infections, in classrooms, laboratories, or clinics.

“The editors of this tour de force of urinary tract biology have recruited the field’s top thought leaders to contribute chapters covering all aspects of the discipline. This outstanding text encompasses everything from the newest theories regarding basic pathogenesis of urinary tract infections, to broad insights into the epidemiology of bacterial uropathogens, and the latest in translational research on new vaccine and therapeutic candidates,” said Michael Hsieh, MD, PhD, Stirewalt Endowed Director, Biomedical Research Institute; PI, Schistosomiasis Resource Center and The Bladder Immunology Group (BIG); Associate Professor of Urology and Pediatrics, George Washington University; Director, CAPITUL, Children’s National Medical Center.

About the editors of Urinary Tract Infections: Molecular Pathogenesis and Clinical Management:

MATTHEW A. MULVEY received his PhD from the University of Texas at Austin, followed by postdoctoral training in bacterial pathogenesis at Washington University School of Medicine. Dr. Mulvey is currently a professor in the Department of Pathology, Division of Microbiology and Immunology at the University of Utah School of Medicine. His lab works to understand the virulence mechanisms used by uropathogenic Escherichia coli and related pathogens, with the goal of developing improved therapeutics.

DAVID J. KLUMPP received his PhD at Northwestern University in retinal neuron physiology in 1994. As an NIAID fellow, he next studied epithelial biology and the pathogenesis of human papillomaviruses at the Feinberg School of Medicine at Northwestern University. In 1998, he joined the Department of Urology in the Feinberg School of Medicine where he is Associate Professor and the Anthony J. Schaeffer MD Professor in Urology. His lab studies mechanisms of bladder inflammation and pelvic pain and seeks to develop microbial therapies for pain.

ANN E. STAPLETON earned her undergraduate degree at Harvard University and her medical degree at the Albert Einstein College of Medicine. Her postgraduate training was completed at the University of California San Francisco and the University of Washington under the mentorship of Dr. Walter Stamm in the laboratories of Dr. Steve Moseley and Dr. Sen-itiroh Hakomori. Dr. Stapleton is a professor in the Department of Medicine, Division of Allergy and Infectious Diseases at the University of Washington. Her lab and research group study clinical and translational aspects of the pathogenesis, treatment, and prevention of urinary tract infections.

Urinary Tract Infections: Molecular Pathogenesis and Clinical Management is available on ASM Science for $150.00.


ASM Press is the book publishing arm of the American Society for Microbiology (ASM), the oldest and largest single life science membership organization in the world. The ASM's mission is to promote research in the microbial sciences and to assist communication between scientists, policy makers, and the public to improve health and foster economic well-being.

For more information, please contact Courtenay S. Brown, ASM Press Sales and Marketing Manager (202-942-9316, csbrown@asmusa.org).