Nov. 19 SessionRegistration opens Nov. 1.
The selected study evaluates SARS-CoV-2 evasion of the immune response and identifies the viral proteins that antagonize type I interferon (IFN-I) response. The study provides new insights on the mechanism of how this virus evades the host immune response and its potential impact on viral transmission and pathogenesis. Our presenter and panelists, with their diverse expertise, will lead an in-depth discussion of how different SARS-CoV-2 proteins inhibit IFN-I response through distinct mechanisms. Also, the panel will discuss how SARS-CoV, SARS-CoV-2 and MERS-CoV proteins inhibit IFN-I at different efficacies.
Evasion of Type I Interferon by SARS-CoV-2
Authors: Hongjie Xia, Zengguo Cao, Xuping Xie, Xianwen Zhang, John Yun-Chung Chen, Hualei Wang, Vineet D. Menachery, Ricardo Rajsbaum, and Pei-Yong Shi
Cell Reports Oct 2020, 33 (1)
Copyright © 2020 the Author(s).
This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY).
Christopher Basler, Ph.D.
Center for Microbial Pathogenesis, Institute for Biomedical Sciences at Georgia State University
Rozanne Sandri-Goldin, Ph.D.
University of California Irvine
Jan. 21, 2020, 2 p.m. EDT (registration will open Jan. 1)
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