Join research experts in discussing recent journal articles posted to ASM's COVID-19 Research Registry. The Virtual Journal Club sessions are held on the third Thursday of the month at 2 p.m. Eastern Time. Registration for each month's session opens on the first of the month.

Nov. 19 Session

Registration opens Nov. 1.

The selected study evaluates SARS-CoV-2 evasion of the immune response and identifies the viral proteins that antagonize type I interferon (IFN-I) response. The study provides new insights on the mechanism of how this virus evades the host immune response and its potential impact on viral transmission and pathogenesis. Our presenter and panelists, with their diverse expertise, will lead an in-depth discussion of how different SARS-CoV-2 proteins inhibit IFN-I response through distinct mechanisms. Also, the panel will discuss how SARS-CoV, SARS-CoV-2 and MERS-CoV proteins inhibit IFN-I at different efficacies.

Evasion of Type I Interferon by SARS-CoV-2 

Authors: Hongjie Xia, Zengguo Cao, Xuping Xie, Xianwen Zhang, John Yun-Chung Chen, Hualei Wang, Vineet D. Menachery, Ricardo Rajsbaum, and Pei-Yong Shi

Cell Reports Oct 2020, 33 (1)
DOI: 10.1016/j.celrep.2020.108234

Copyright © 2020 the Author(s).
This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY).

Presenter

Christopher Basler, Ph.D. 
Center for Microbial Pathogenesis, Institute for Biomedical Sciences at Georgia State University

Moderator

Rozanne Sandri-Goldin, Ph.D.
University of California Irvine

Discussion Panel

Susan Baker, Ph.D.
Loyola University Chicago

Cornelia Bergmann, Ph.D.
Cleveland Clinic Lerner College of Medicine

Andrew Pekosz, Ph.D.
Johns Hopkins University

Next Session 

Jan. 21, 2020, 2 p.m. EDT (registration will open Jan. 1)

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Contact Information

COVID-19 Registry Team, covid19registry@asmusa.org