Join research experts in discussing recent journal articles posted to ASM's COVID-19 Research Registry. The Virtual Journal Club sessions are held on the third Thursday of the month at 2 p.m. Eastern Time. Registration for each month's session opens on the first of the month.

July 15 Session

Registration opens July 1.

The selected study examines how small molecules bind and inhibit the main protease of SARS-CoV-2. Our presenter and panelists, with their diverse expertise, will lead an in-depth discussion of the findings and explore the impacts of the structure of antivirals to inhibit SARS-CoV-2 proteins.

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L.

Authors: Michael Dominic Sacco, Chunlong Ma, Panagiotis Lagarias, Ang Gao, Julia Alma Townsend, Xiangzhi Meng, Peter Dube, Xiujun Zhang, Yanmei Hu, Naoya Kitamura, Brett Hurst, Bart Tarbet, Michael Thomas Marty, Antonios Kolocouris, Yan Xiang, Yu Chen and Jun Wang.

Science Advances  (2020)
DOI: 10.1126/sciadv.abe0751

Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).


Lynn W. Enquist, Ph.D.

Lynn W. Enquist, Ph.D.

Princeton University


Joyce Jose, Ph.D.
Huck Institutes of the Life Science, The Pennsylvania State University

Discussion Panel

Arnab Chatterjee, Ph.D.
Calibr at Scripps Research

Matthew D. Hall, Ph.D.
National Center for Advancing Translational Sciences, National Institutes of Health

Next Session 

Aug. 19, 2021, 2 p.m. ET (registration will open Aug. 1)

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Recordings are available free to ASM members.

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Registration Details

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Contact Information

COVID-19 Registry Team,