Alexander Lepak, M.D.

Alexander Lepak, M.D.

University of Wisconsin

Alex Lepak is an associate professor at the University of Wisconsin in the Department of Medicine, Division of Infectious Diseases. He is an active physician, educator and researcher. His research pursuits involve performing and translating antimicrobial pharmacodynamic (PD) studies (in vivo animal models and patient-level data) to optimize therapy against numerous pathogens. Specifically, this research has included medically important fungal and bacterial pathogens, including those that are difficult to treat or have drug resistance determinants. An additional area of active study is antimicrobial drug development using in vivo animal models. In collaboration with Dr. Andes, their lab has evaluated hundreds of pre-clinical and clinical compounds. They are internationally recognized for drug development and optimization via PK/PD approaches.
 
Clinically, Lepak provides inpatient and outpatient infectious diseases consultations at UW Health and the Madison Veterans Affairs Hospital. He is the director of antimicrobial stewardship at UW Health. He leads quality improvement and research projects focused on improving antimicrobial and diagnostic test utilization. He is on the editorial board for ASM’s Antimicrobial Agents and Chemotherapy. His leadership and expertise have led to national and international recognition and invitations to guide numerous groups, including USCAST, CLSI, GARDP-REVIVE, ICAAC, ECCMID, ASM, IDSA and the U.S. Food and Drug Administration. You can follow him on Twitter at @a_lepak.