The TWiP team solves the case of the Ghanian Women with Leg Swelling, and relates how Anopheline mosquitoes are protected against parasite infection by tryptophan catabolism in gut microbiota.
Links for This Episode
- Bacteria protect mosquitoes from parasite infection (Nat Microbiol).
- Letters read on TWiP 206.
Case Study for TWiP 206
42 yo Spanish-speaking male, originally from capital city of Honduras. Admitted to hospital after seizure. Grew up in Honduras, 20-year history of seizures. Now in NYC area. Treated with carbamazepine, 2x a day. Has not filled scrip for 3 months. Fast heartrate, o2 sat fine, no fever. No surgery, no toxic habits. Unremarkable physical exam. Undergoes blood work and head imaging. CBC normal, normal diff, slight elevation in blood glucose. Imaging of head reveals non-specific coarse calcification. Eats regularly.
Send your case diagnosis, questions and comments to twip@microbe.tv
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Music by Ronald Jenkees.